(at around 23 mins) In this film, Drax refuses to share his zarg nuts with Mantis. This is because in The Guardians of the Galaxy Holiday Special (2022), she ate all of his without permission.

This film sets the record for the most makeup appliances used in a single film. The numbers are staggering, totaling 22,541 prosthetics, 500 wigs, and 117 pairs of contacts by the end, used across more than 1,000 actors.

Nebula has a new nano tech weave arm in this film, which was an upgrade made for her by Rocket. Director James Gunn confirmed Rocket made this arm for Nebula to thank her for gifting him Bucky's detached vibranium arm in The Guardians of the Galaxy Holiday Special (2022).

After James Gunn was fired as director, actor Dave Bautista (Drax) became one of Gunn's most vocal supporters, tweeting that "James Gunn is one of the most loving, caring, good natured people I have ever met. He's gentle and kind and cares deeply for people and animals. He's made mistakes. We all have. I'm NOT ok with what's happening to him." Bautista even stated that he would demand to be released from his contract if the studio did not use the screenplay Gunn had originally written for this film. Gunn was later re-hired.

Taika Waititi was widely rumored to take over directing from James Gunn after the latter was temporarily fired from the project. However, Waititi made it clear that this option was never on the table for him, claiming that "those are James' films. [That] would be like going into someone's house and saying 'Hey, I'm your new dad, and this is how we make peanut butter sandwiches now.' It feels kind of awkward."

Factual errors

In the closing credits for Special Thanks, Bobcat Goldthwait's last name is misspelled as "Goldthwaite."

Every species of animals who goes through the High Evolutionary's "millions of years of evolution" process end up humanoids, which is a very anthropocentric clich?.



Revealing mistakes

(at around 1h 12 mins) When the girl is running in loops for the High Evolutionary, her long hair does not fall down towards the floor when she is upside down. It stays in place behind her shoulders (defying gravity).



Plot holes

The two ships have a huge hole on their sides and yet no one is affected by the vacuum of space unless they "step outside".

(at around 1h 40 mins) The creatures on Counter Earth are mostly evolved from mammals, but one of them is clearly of avian origin; she has breasts, which only mammals have.



Character error

(at around 57 mins) Smart survivor Gamora gives away her location to a stranger despite obviously not recognizing their voice.

(at around 1h 30 mins) Not the best move to remove an electronic piece of equipment in water. It could then very easily malfunction.

The High Evolutionary needs Rocket's brains and yet sends a rookie who traumatizes him.

(at around 5 mins) These heroes should know never to put to bed an intoxicated person on their backs but always in the recovery position.

(at around 1h 45 mins) Rocket doesn't try and shoot down the flying robots coming at him.